Simon Pascal

Localisation

TPR1 - 5 étage

Grade

CRCN

Fonction

chercheur

Pièce

G.05.15

pascal.jpg

Activité

Organic/coordination chemistry, chirality, charged chromophores, near-infrared dyes, spectroscopy, nonlinear optics

Thèmes

Organic Synthesis - Coordination Chemistry - Chirality - Near-Infrared Dyes - Spectroscopy - Nonlinear Optics

 

Recherche

Key publications:

"Small Panchromatic and NIR Absorbers from Quinoid Zwitterions" Org. Lett. 2020, 22, 7997-8001

"Fused Bis-Azacalixphyrin that reaches NIR-II absorptions" Chem. Commun. 2020, 56, 896-899

"Azacalixphyrins as NIR Photoacoustic Contrast Agents" Chem. Commun. 2018, 54, 12365-12368

"Controlling the Canonical/Zwitterionic Balance through Intramolecular Proton Transfer: a Strategy for Vapochromism" Mater. Chem. Front. 2018, 2, 1618-1625

"Design of Near-Infrared-Absorbing Unsymmetrical Polymethine Dyes with Large Quadratic Hyperpolarizabilities" Chem. Mater. 2018, 30, 34103418.

"Keto-polymethines: a versatile class of dyes with outstanding spectroscopic properties for in cellulo and in vivo two-photon microscopy imaging" Chem. Sci. 2017, 8, 381394

"Functionalized cationic [4]helicenes with unique tuning of absorption, fluorescence and chiroptical properties up to the far-red range" Chem. Sci. 2016, 7, 46854693

 

Parcours

S. P. obtained his PhD in chemistry in 2014 (ENS Lyon), developing NIR polymethine dyes for applications in the field of nonlinear optics (defense, imaging, organic electronics). After two years at the University of Geneva, working on the synthesis of cationic helicene dyes and the study of their (chir)optical properties, he was appointed Chargé de Recherche CNRS in the chemistry department at CINaM (Dec. 2016). Dr. Pascal is specialized in the synthesis of charged NIR chromophores and possesses a wide expertise in their applications as materials for emerging technologies. He is the author of more than 40 publications at the frontier between organic chemistry, spectroscopy and biology.

Publications

2020

Mixed N-Aryl/Alkyl Substitution Favours an Unusual Tautomer of Near-Infrared Absorbing Azacalixphyrins

Lucien Lavaud, Cloé Azarias, Gabriel Canard, Simon Pascal, Denis Jacquemin, Olivier Siri

New Journal of Chemistry (2020)10.1039/D0NJ04587J

Near-Infrared Electrochemiluminescence in Water through Regioselective Sulfonation of Diaza [4] and [6]helicene Dyes

Haidong Li, Romain Duwald, Simon Pascal, Silvia Voci, Céline Besnard, Johann Bosson, Laurent Bouffier, Jérôme Lacour, Neso Sojic

Chemical Communications (2020)10.1039/D0CC04156D

Stabilization of a 12-π electrons diamino-benzoquinonediimine tautomer

Jean-François Longevial, Zhongrui Chen, Simon Pascal, Gabriel Canard, Denis Jacquemin, Olivier Siri

Chemical Communications (2020)10.1039/D0CC06815B

Synthesis, Resolution, Configurational Stability, and Properties of Cationic Functionalized [5]Helicenes

Maya Marinova, Simon Pascal, Laure Guénée, Céline Besnard, Boris Shivachev, Kalina Kostova, Claudio Villani, Roberta Franzini, Vladimir Dimitrov, Jérôme Lacour

Journal of Organic Chemistry (2020)10.1021/acs.joc.0c01716

Impacts of Ion‐Pairing Effects on Linear and Nonlinear Photophysical Properties of Polymethines Dyes

Simon Pascal, San-Hui Chi, Joseph Perry, Chantal Andraud, Olivier Maury, S.-H Chi

ChemPhysChem (2020)10.1002/cphc.202000731

Small Panchromatic and NIR Absorbers from Quinoid Zwitterions

Angélina Torres Ruiz, Manon Bousquet, Simon Pascal, Gabriel Canard, Valérie Mazan, Mourad Elhabiri, Denis Jacquemin, Olivier Siri

Organic Letters (2020)10.1021/acs.orglett.0c02926

1D Coordination π‐d Conjugated Polymers with Distinct Structures Defined by the Choice of the Transition Metal: Towards a New Class of Antiaromatic Macrocycles

Vijai Meena Santhini, Christian Wäckerlin, Ales Cahlik, Martin Ondráček, Simon Pascal, Adam Matěj, Oleksandr Stetsovych, Pingo Mutombo, Petr Lazar, Olivier Siri, Pavel Jelinek

Angewandte Chemie International Edition (2020)10.1002/anie.202011462

2019

Versatile transamination in quinonediimine chemistry: Towards a novel class of water soluble UV/violet chromophores

Zhongrui Chen, Maxime Bert, Simon Pascal, Gabriel Canard, Olivier Siri

Tetrahedron Letters 151024 (2019)10.1016/j.tetlet.2019.151024

Merging polyacenes and cationic helicenes: from weak to intense chiroptical properties in the far red region

Romain Duwald, Johann Bosson, Simon Pascal, Stephane Grass, Francesco Zinna, Céline Besnard, Lorenzo Di Bari, Denis Jacquemin, Jérôme Lacour

Chemical Science (2019)10.1039/C9SC05407C

First Principles Investigation of the Spectral Properties of Neutral, Zwitterionic, and bis-Cationic Azaacenes

Patricia Guevara-Level, Simon Pascal, Olivier Siri, Denis Jacquemin

Physical Chemistry Chemical Physics (2019)10.1039/C9CP04835A

Fused Bis-Azacalixphyrin that reaches NIR II absorptions

Lucien Lavaud, Cloe Azarias, Gabriel Canard, Simon Pascal, Joachim Galiana, Michel Giorgi, Zhongrui Chen, Denis Jacquemin, Olivier Siri

Chemical Communications (2019)10.1039/C9CC09021E

Azacalixquinarenes: From Canonical to (Poly-)Zwitterionic Macrocycles

Simon Pascal, Lucien Lavaud, Cloé Azarias, Alexandre Varlot, Gabriel Canard, Michel Giorgi, Denis Jacquemin, Olivier Siri

Journal of Organic Chemistry 84:1387-1397 (2019)10.1021/acs.joc.8b02847

Unraveling the Two-Photon and Excited State Absorptions of Aza-BODIPY Dyes for Optical Power Limiting in the SWIR Band

Simon Pascal, Quentin Bellier, Sylvain David, Pierre-Antoine Bouit, San-Hui Chi, Nikolay Makarov, Boris Le Guennic, Siwar Chibani, Gérard Berginc, Patrick Feneyrou, Denis Jacquemin, Joseph Perry, Olivier Maury, Chantal Andraud

Journal of Physical Chemistry C 123:23661-23673 (2019)10.1021/acs.jpcc.9b08376

Synthesis of new cyanine-labeled bacterial lipooligosaccharides for intracellular imaging and in vitro microscopy studies

Tung-Cheng Wang, Florent Cochet, Fabio Alessandro Facchini, Lenny Zaffaroni, Christelle Serba, Simon Pascal, Andrea Sala, Chantal Andraud, Flaviana Di Lorenzo, Olivier Maury, Thomas Huser, Francesco Peri

Bioconjugate Chemistry (2019)10.1021/acs.bioconjchem.9b00044

2018

Central substitution of azacalixphyrins: a strategy towards acidochromic NIR dyes

Cloé Azarias, Simon Pascal, Olivier Siri, Denis Jacquemin

Physical Chemistry Chemical Physics 20:20056-20069 (2018)10.1039/c8cp03789b

Specific labeling of mitochondria of Chlamydomonas with cationic helicene fluorophores

Christoph Bauer, Romain Duwald, Geraldine Maria Labrador, Simon Pascal, Pau Moneva Lorente, Johann Bosson, Jérôme Lacour, Jean-David Rochaix

Organic and Biomolecular Chemistry 16:919-923 (2018)10.1039/C7OB02906C

C-Functionalized Cationic Diazaoxatriangulenes: Late-Stage Synthesis and Tuning of Physicochemical Properties

Irene Hernández Delgado, Simon Pascal, Céline Besnard, Silvia Voci, Laurent Bouffier, Néso Sojic, Jérôme Lacour

Chemistry - A European Journal 24:10186-10195 (2018)

Combined reversible switching of ECD and quenching of CPL with chiral fluorescent macrocycles

Alexandre Homberg, Elodie Brun, Francesco Zinna, Simon Pascal, Marcin Górecki, Luc Monnier, Céline Besnard, Gennaro Pescitelli, Lorenzo Di Bari, Jérôme Lacour

Chemical Science 9:7043-7052 (2018)10.1039/C8SC02935K

Azacalixphyrins as NIR photoacoustic contrast agents

Lucien Lavaud, Simon Pascal, Khaled Metwally, Damien Gasteau, Anabela da Silva, Zhongrui Chen, Mourad Elhabiri, Gabriel Canard, Denis Jacquemin, Olivier Siri

Chemical Communications 54:12365-12368 (2018)10.1039/C8CC05851B

C-Functionalized Cationic Diazaoxatriangulenes: Late-Stage Synthesis and Tuning of Physicochemical Properties

Simon Pascal, Irene Hernández Delgado, Céline Besnard, Silvia Voci, Laurent Bouffier, Neso Sojic, Jérôme Lacour

Chemistry - A European Journal 24:10186-10195 (2018)10.1002/chem.201801486

Controlling the canonical/zwitterionic balance through intramolecular proton transfer: a strategy for vapochromism

Simon Pascal, Lucien Lavaud, Cloé Azarias, Gabriel Canard, Michel Giorgi, Denis Jacquemin, Olivier Siri

Materials Chemistry Frontiers 2:1618-1625 (2018)10.1039/C8QM00171E

Design of Near-Infrared-Absorbing Unsymmetrical Polymethine Dyes with Large Quadratic Hyperpolarizabilities

Simon Pascal, Yulia Getmanenko, Yadong Zhang, Iryna Davydenko, Minh Hoang Ngo, Guillaume Pilet, Sébastien Redon, Yann Bretonniere, Olivier Maury, Isabelle Ledoux-Rak, Stephen Barlow, Seth Marder, Chantal Andraud

Chemistry of Materials 30:3410-3418 (2018)10.1021/acs.chemmater.8b00960

2017

[4]Helicene-Squalene Fluorescent Nanoassemblies for Specific Targeting of Mitochondria in Live-Cell Imaging

Andrej Babič, Simon Pascal, Romain Duwald, Dimitri Moreau, Jérôme Lacour, Eric Allémann

Advanced Functional Materials 27:1701839 (2017)10.1002/adfm.201701839

Enantiospecific Elongation of Cationic Helicenes by Electrophilic Functionalization at Terminal Ends

Romain Duwald, Simon Pascal, Johann Bosson, Stephane Grass, Céline Besnard, Thomas Bürgi, Jérôme Lacour

Chemistry - A European Journal 23:13596-13601 (2017)10.1002/chem.201703441

Efficient Annihilation Electrochemiluminescence of Cationic Helicene Luminophores

Haidong Li, Silvia Voci, Antoine Wallabregue, C. Adam, Geraldine Labrador, Romain Duwald, Irene Hernández delgado, Simon Pascal, Johann Bosson, Jérôme Lacour, Laurent Bouffier, Néso Sojic

ChemElectroChem 4:1750-1756 (2017)10.1002/celc.201600906

Benzoquinonediimine ligands: Synthesis, coordination chemistry and properties

Simon Pascal, Olivier Siri

Coordination Chemistry Reviews 350:178-195 (2017)10.1016/j.ccr.2017.06.015

Keto-polymethines: a versatile class of dyes with outstanding spectroscopic properties for in cellulo and in vivo two-photon microscopy imaging

Simon Pascal, Sandrine Denis-Quanquin, Florence Appaix, Alain Duperray, Alexei Grichine, Boris Le Guennic, Denis Jacquemin, Jérôme Cuny, San-Hui Chi, Joseph W. Perry, Boudewijn van der Sanden, Cyrille Monnereau, Chantal Andraud, Olivier Maury

Chemical Science 8:381-394 (2017)10.1039/C6SC02488B

Excimer-Based On-Off Bis(pyreneamide) Macrocyclic Chemosensors

Mahesh Vishe, Timothée Lathion, Simon Pascal, Oleksandr Yushchenko, Alexandre Homberg, Elodie Brun, Eric Vauthey, Claude Piguet, Jérôme Lacour

Helvetica Chimica Acta 101:e1700265 (2017)10.1002/hlca.201700265

2016

Synthesis and electronic properties of polycyclic aromatic hydrocarbons doped with phosphorus and sulfur

W. Delaunay, R. Szűcs, Simon Pascal, A. Mocanu, Pierre-Antoine Bouit, L. Nyulászi, M. Hissler

Dalton Transactions 45:1896-1903 (2016)10.1039/C5DT04154F

Functionalized cationic [4]helicenes with unique tuning of absorption, fluorescence and chiroptical properties up to the far-red range

Simon Pascal, I. Hernández Delgado, A. Wallabregue, R. Duwald, C. Besnard, L. Guénée, C. Nançoz, E. Vauthey, R. Tovar, J. Lunkley, G. Muller, J. Lacour

Chemical Science 7:4685-4693 (2016)10.1039/C6SC00614K