Anne Charrier
TPR1 - 3 étage
DR2
chercheur
G.03.22
From molecular variations to macroscopic properties
Our research activity focuses on studying multiscale effects to understand how small variations at the molecular or molecular assembly level impart specific physical properties to the macroscopic systems they constitute, which properties are then utilized in technological applications. Our research is divided into three distinct thematics: 1) Thin films field-effect transistor sensors. 2) Dynamics of red blood cells under flow. 3) Wood cell wall at the nanoscale.
Our activity is based on a deep intertwining of fundamental and applied research. From a fundamental perspective, we are interested in the relationship between chemical nature, structural organization, and physical properties to answer the question: how do small variations at the molecular level impact the physical properties (electrical, mechanical, structural) of assemblies constituted at the macroscopic scale?
Our work on applicative development falls into two main axes: (i) innovative sensors for ion detection in solution. (ii) functional and/or microfluidic platforms for studying cell behavior and their properties (red blood cell mechanics).
For further details, please visit our WEBSITE.
2024
Substrate stiffness alters layer architecture and biophysics of human induced pluripotent stem cells to modulate their differentiation potential
Jack Llewellyn, Anne Charrier, Rossana Cuciniello, Emmanuèle Helfer, Rosanna Dono
iScience 27:110557 (2024)10.1016/j.isci.2024.110557
2023
Classification of red cell dynamics with convolutional and recurrent neural networks: a sickle cell disease case study
Maxime Darrin, Ashwin Samudre, Maxime Sahun, Scott Atwell, Catherine Badens, Anne Charrier, Emmanuèle Helfer, Annie Viallat, Vincent Cohen-Addad, Sophie Giffard-Roisin
Scientific Reports 13:745 (2023)10.1038/s41598-023-27718-w
Physical mechanisms of red blood cell splenic filtration
Alexis Moreau, François Yaya, Huije Lu, Anagha Surendranath, Anne Charrier, Benoit Dehapiot, Emmanuèle Helfer, Annie Viallat, Zhangli Peng
Proceedings of the National Academy of Sciences of the United States of America (2023)10.1101/2023.01.10.523245
2022
Dynamics of Individual Red Blood Cells Under Shear Flow: A Way to Discriminate Deformability Alterations
Scott Atwell, Catherine Badens, Anne Charrier, Emmanuèle Helfer, Annie Viallat
Frontiers in Physiology 12 (2022)10.3389/fphys.2021.775584
Affinity driven ion exchange EG-OFET sensor for high selectivity and low limit of detection of Cesium in seawater
Tin Phan Nguy, Volkan Kilinc, Ryoma Hayakawa, Catherine Henry-De-Villeneuve, Jean-Manuel Raimundo, Yutaka Wakayama, Anne Charrier
Sensors and Actuators B: Chemical 351:130956 (2022)10.1016/j.snb.2021.130956
2021
In situ plant materials hyperspectral imaging by multimodal scattering near-field optical microscopy
Anne Charrier, Aubin C Normand, Ali Passian, Philip Schaefer, Aude L. L. Lereu
Communications Materials 2:59 (2021)10.1038/s43246-021-00166-7
Influence of force volume indentation parameters and processing method in wood cell walls nanomechanical studies
Aubin C Normand, Anne Charrier, Olivier Arnould, Aude L. Lereu
Scientific Reports 11:5739 (2021)10.1038/s41598-021-84994-0
2020
Nanomechanics and Raman Spectroscopy of in Situ Native Carbohydrate Storage Granules for Enhancing Starch Quality and Lignocellulosic Biomass Production
Rubye Farahi, Aude L. Lereu, Anne Charrier, Udaya C Kalluri, Brian H Davison, Ali Passian
ACS Omega 5:2594−2602 (2020)10.1021/acsomega.9b02849
Femtomolar detection of Cu2+ ions in solution using super-Nernstian FET-sensor with a lipid monolayer as top-gate dielectric
A. Kenaan, F. Brunel, J.-M. Raimundo, Anne Charrier
Sensors and Actuators B: Chemical 316:128147 (2020)10.1016/j.snb.2020.128147
Electrolyte-gated-organic field effect transistors functionalized by lipid monolayers with tunable pH sensitivity for sensor applications
Tin Phan Nguy, Ryoma Hayakawa, Volkan Kilinc, Matthieu Petit, Yemineni S L V Narayana, Masayoshi Higuchi, Jean-Manuel Raimundo, Anne Charrier, Yutaka Wakayama
Applied Physics Express 13:011005 (2020)10.7567/1882-0786/ab5322
2019
Self-organization of red blood cell suspensions under confined 2D flows
Cécile Iss, Dorian Midou, Alexis Moreau, Delphine Held, Anne Charrier, Simon Mendez, Annie Viallat, Emmanuèle Helfer
Soft Matter (2019)10.1039/C8SM02571A
Novel and Innovative Interface as Potential Active Layer in Chem-FET Sensor Devices for the Specific Sensing of Cs+
Volkan Kilinc, Catherine Henry-De-Villeneuve, Tin Phan Nguy, Yutaka Wakayama, Anne M Charrier, Jean-Manuel Raimundo
ACS Applied Materials & Interfaces 11:47635-47641 (2019)10.1021/acsami.9b18188
Stable operation of water-gated organic field-effect transistor depending on channel flatness, electrode metals and surface treatment
Tin Phan Nguy, Ryoma Hayakawa, Volkan Kilinc, Matthieu Petit, Jean-Manuel Raimundo, Anne Charrier, Yutaka Wakayama
Japanese Journal of Applied Physics 58:SDDH02 (2019)10.7567/1347-4065/ab09d2
2018
Nanometrology of Biomass for Bioenergy: The Role of Atomic Force Microscopy and Spectroscopy in Plant Cell Characterization
Anne Charrier, Aude L. Lereu, Rubye Farahi, Brian Davison, Ali Passian
Frontiers in Energy Research 6:11 (2018)10.3389/fenrg.2018.00011
Facile Nanopatterning of PEDOT:PSS Thin Films
Mohammed Elmahmoudy, Anne Charrier, George G. Malliaras, Sébastien Sanaur
Advanced Materials Technologies 3:1700344 (2018)10.1002/admt.201700344
Ultra-thin supported lipid monolayer with unprecedented mechanical and dielectric properties
Ahmad Kenaan, Racha El Zein, Volkan Kilinc, Sébastien Lamant, Jean-Manuel Raimundo, Anne Charrier
Advanced Functional Materials 1801024 (2018)10.1002/adfm.201801024
2017
Printing functional protein nano-dots on soft elastomers: from transfer mechanism to cell mechanosensing
Ranime Alameddine, Astrid Wahl, Fuwei Pi, Kaoutar Bouzalmate, Laurent Limozin, Anne Charrier, Kheya Sengupta
Nano Letters 17:4284-4290 (2017)10.1021/acs.nanolett.7b01254
Ligand Nano-cluster Arrays in a Supported Lipid Bilayer
Emmanuelle Benard, Fuwei Pi, Igor Ozerov, Anne Charrier, Kheya Sengupta
Journal of visualized experiments : JoVE 122:e55060 (2017)10.3791/55060
Tailoring the electrochemical and mechanical properties of PEDOT : pss films for bioelectronics
Mohammed H Elmahmoudy, Sahika Inal, Anne Charrier, Ilke Uguz, George Malliaras, Sébastien Sanaur
Macromolecular Materials and Engineering 302 (2017)10.1002/mame.201600497
Plasticity, elasticity, and adhesion energy of plant cell walls: nanometrology of lignin loss using atomic force microscopy
R. H Farahi, Anne Charrier, A. Tolbert, A. Lereu, A. Ragauskas, B. Davison, A. Passian
Scientific Reports 7 (2017)10.1038/s41598-017-00234-4
High Aspect Ratio Sub-Micrometer Channels Using Wet Etching: Application to the Dynamics of Red Blood Cell Transiting through Biomimetic Splenic Slits
Priya Gambhire, Scott Atwell, Cécile Iss, Frédéric Bedu, Igor Ozerov, Catherine Badens, Emmanuèle Helfer, Annie Viallat, Anne Charrier
Small 13:1700967 (2017)10.1002/smll.201700967
2016
Subpicomolar Iron Sensing Platform Based on Functional Lipid Monolayer Microarrays
Ahmad Kenaan, Tuyen D. Nguyen, Herve Dallaporta, Jean-Manuel Raimundo, Anne M. Charrier
Analytical Chemistry 88:3804-3809 (2016)10.1021/acs.analchem.5b04834
2015
Size-Tunable Organic Nanodot Arrays: A Versatile Platform for Manipulating and Imaging Cells
Fuwei Pi, Pierre Dillard, Ranime Alameddine, Emmanuelle Benard, Astrid Wahl, Igor Ozerov, Anne Charrier, Laurent Limozin, Kheya Sengupta
Nano Letters 15:5178-5184 (2015)10.1021/acs.nanolett.5b01400
2014
Mechanical characterization of cross-linked serum albumin microcapsules
Clément de Loubens, Julien Deschamps, Marc Georgelin, Anne Charrier, Florence Edwards-Levy, Marc Leonetti
Soft Matter 10:4561-4568 (2014)10.139/C4SM00349G
A field effect transistor biosensor with a γ-pyrone derivative engineered lipid-sensing layer for ultrasensitive Fe3+ion detection with low pH interference
T.-D. Nguyen, A. Labed, R. El Zein, S. Lavandier, F. Bedu, I. Ozerov, H. Dallaporta, J.-M. Raimundo, A.M. Charrier
Biosensors and Bioelectronics 54:571-577 (2014)10.1016/j.bios.2013.11.051
2013
Determination of mechanical properties of cortical bone using AFM under dry and immersed conditions
Emmanuelle Lefevre, Carine Guivier-Curien, Martine Pithioux, Anne Charrier
Computer Methods in Biomechanics and Biomedical Engineering 16:337-339 (2013)10.1080/10255842.2013.815974
Nanometric Protein-Patch Arrays on Glass and Polydimethylsiloxane for Cell Adhesion Studies
Fuwei Pi, Pierre Dillard, Laurent Limozin, Anne Charrier, Kheya Sengupta
Nano Letters 13:3372-3378 (2013)10.1021/nl401696m
2012
Wetting Properties and Critical Micellar Concentration of Benzalkonium Chloride Mixed in Sodium Hypochlorite
F. Bukiet, G. Couderc, J. Camps, H. Tassery, F. Cuisinier, I. About, A. Charrier, N. Candoni
Supported Lipid Monolayer with Improved Nanomechanical Stability: Effect of Polymerization
R. Elzein, H. Dallaporta, A.M. Charrier
Label free femtomolar electrical detection of Fe(III) ions with a pyridinone modified lipid monolayer as the active sensing layer
T. Nguyen Duc, R. Elzein, J-M. Raimundo, H. Dallaporta, A.M. Charrier