Jing Ma, Shashwati Kala, Susan Yung, Tak Mao Chan, Yu Cao, Yifan Jiang, Xiaoxuan Liu, Suzanne Giorgio, Ling Peng, and Alice ST Wong Mol. Ther., 2018, 26, 70-83 Metastasis is the cause of most (>90%) cancer deaths, and currently lack of effective treatments. In this study, we demonstrate the potential advantages of using rationally designed