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Highlights

05 July 2019

Flavonoid-Alkylphospholipid Conjugates Elicit Dual Inhibition of Cancer Cell Growth and Lipid Accumulation

A new publication from IMMF departement in Chemical Communications

24 June 2019

Many-body perturbation theory calculations using the yambo code

Yambo [1] is an open-source ab-initio software suitable to calculate and predict electronic and optical properties of materials and low-dimensional structures, including their electronic band-structures and optical response to light interaction.

24 June 2019

Efficient and Innocuous Delivery of siRNA to Microglia using an Amphiphilic Dendrimer Nanovector

The “Biomolecules and Biomaterials” team discovers that amphiphilic dendrimers can efficiently deliver siRNA to Microglia

02 May 2019

Biphasic mechanosensitivity of T cell receptor-mediated spreading of lymphocytes

A. Wahl, C. Dinet, P. Dillard, A. Nassereddine, P-H. Puech, L. Limozin & K. SenguptA. PNAS 2019 116 (13) 5908-5913.

10 April 2019

Solubility and Microfluidic

This communication presents a new microfluidics device for solubility measurement based on the generation of saturated solutions starting from powder and compatible with all solvents and molecules

Guillem Peybernès, Romain Grossier, Frédéric Villard, Philippe Letellier, Mehdi Lagaize, Nadine Candoni, Stéphane Veesler
Organic Process Research and Development 22:1856-1860 (2018)10.1021

09 April 2019

Self-organization of red blood cell suspensions under confined 2D flows

In an article published in Soft Matter, the PIV Department shows that healthy red blood cells flowing in microchannels self-align in files. By combining in-vitro and in-silico experiments,

01 April 2019

Estimating single molecule conductance from spontaneous evolution of a molecular contact

H. Klein, SSP. Publication of an original method to estimate the conductance of a single molecule using a Mechanically controlled break junction

01 April 2019

Blocking stemness and metastatic properties of ovarian cancer cells by targeting p70S6K with dendrimer nanovector-based siRNA delivery

Jing Ma, Shashwati Kala, Susan Yung, Tak Mao Chan, Yu Cao, Yifan Jiang, Xiaoxuan Liu, Suzanne Giorgio, Ling Peng, and Alice ST Wong Mol. Ther., 2018, 26, 70-83 Metastasis is the cause of most (>90%) cancer deaths, and currently lack of effective treatments. In this study, we demonstrate the potential advantages of using rationally designed

07 February 2019

Azacalixquinarenes : From Canonical to (Poly-)Zwitterionic Macrocycles

The Siri team publishes in the Journal of Organic Chemistry “Azacalixquinaranènes: From Canonical Macrocycles to (Poly) Zwitterionic Macrocycles”.

31 January 2019

A dual targeting dendrimer-mediated siRNA delivery system for effective gene silencing in cancer therapy

The Peng team publishes in J. Am. Chem. Soc. “A dual targeting dendrimer-mediated siRNA delivery system for effective gene silencing in cancer therapy”.

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