en

Nano SPM

Leader: Clemens Barth

Introduction

The NanoSPM group (Nanoparticles, oxides and SPM) has a long-time experience in the characterization of insulating (oxide) surfaces (bulk and thin film material) and supported metal nanoparticles (NP), which are studied by scanning tunneling microscopy (STM), and in particular by noncontact AFM (nc-AFM) and Kelvin probe force microscopy (KPFM). The morphology, atomic structure, defects and charge state of oxide and related surfaces (MgO, Al2O3, CeOx (ceria), alkali halides) and the morphology, structure and charge state of supported metal NPs (e.g., PdNPs, AuNPs) have been studied in the past. Lateral and charge manipulation experiments at NPs have been also involved.

The second and smaller research field is located in the self-assembly of molecules on insulating surfaces. Mechanisms of adsorption, desorption and self-assembly of (functionalized) molecules (functionalized [5]helicene molecules and C60) have been studied in particular on the surfaces of pure and doped bulk alkali halide crystals.

Nanoparticules, oxides et scanning probe microscopy 1
(a-c) KPFM images of PdNPs on HOPG. A dark contrast corresponds to a low WF and a bright contrast to a high WF. (a) 40nm large NPs after a 14-day exposure of the NPs to the residual gas in the UHV. In particular, carbon contaminates the NPs, lowering the NPs’ WF even below the WF level of HOPG (→ dark contrast). (b) PdNPs that are on the way to get contaminated. Smaller NPs react faster (dark) than large ones (bright). (c) An annealing in O2 at 500°C ’cleans’ contaminated NPs such that the initially high WF of Pd is restored (→ bright contrast). (d) Model of carbon contamination.
Today

The group focuses on topics of heterogeneous model catalysis, in particular on the catalytic activity of metal NPs, which is characterized via analyzing the NP’s work function (WF)  by KPFM. The adsorption, desorption and reactions of reactant and product molecules at NPs are studied, as well as adsorption and dissolution phenomena of carbon on and inside NPs. See Figure 2 and 3, which exemplify carbon contamination phenomena and graphene on NPs, respectively.

Nanoparticules, oxides et scanning probe microscopy 2
The top (111) facets of graphene encapsulated palladium nanoparticles (G@PdNPs) on the HOPG surface (STM topography images). The graphene was synthesized on the pre-grown PdNPs by decomposing C2H4 at 650°C. (a) A selection of G@PdNPs, (b) Image with atomic resolution acquired on NP II.

Group leader

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Clemens Barth

University Lecturer

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Suzanne Giorgio

Publications

2023

Characterizing the Water Forming Reaction on Graphite and Ceria Supported Palladium Nanoparticles and Nanoislands by the Work Function

Baptiste Chatelain, Ali El Barraj, Carine Laffon, Philippe Parent, Clemens Barth

Journal of Physical Chemistry C 127:5731-5742 (2023)10.1021/acs.jpcc.2c08447

Synthesis and antimicrobial testing of 5‐fluorouracil derivatives

Mrunal Patil, Krykun Serhii, Frédéric Garzino, Quentin Gobert, Suzanne Giorgio, Jean‐manuel Raimundo, Jean‐michel Bolla, Michel Camplo

Archiv der Pharmazie / Chemistry in Life Sciences 356 (2023)10.1002/ardp.202300103

2021

Collective amplification of nearby nanoparticles in the Coulomb blockade restricted charging of a single nanoparticle

Baptiste Chatelain, Ali El Barraj, Clémence Badie, Lionel Santinacci, Clemens Barth

New Journal of Physics (2021)10.1088/1367-2630/ac38cb

An ionizable supramolecular dendrimer nanosystem for effective siRNA delivery with a favorable safety profile

Dinesh Dhumal, Wenjun Lan, Ling Ding, Yifan Jiang, Zhenbin Lyu, Erik Laurini, Domenico Marson, Aura Tintaru, Nelson Dusetti, Suzanne Giorgio, Juan Lucio Iovanna, Sabrina Pricl, Ling Peng

Nano Research (2021)10.1007/s12274-020-3216-8

High-temperature oxidation and reduction of the inverse ceria/Cu(111) catalyst characterized by LEED, STM, nc-AFM and KPFM

Ali El Barraj, Baptiste Chatelain, Clemens Barth

Journal of Physics: Condensed Matter (2021)10.1088/1361-648X/ac26f9

2020

A self-assembling amphiphilic dendrimer nanotracer for SPECT imaging

Ling Ding, Zhenbin Lyu, Aura Tintaru, Erik Laurini, Domenico Marson, Beatrice Louis, Ahlem Bouhlel, Laure Balasse, Samantha Fernandez, Philippe Garrigue, Eric Mas, Suzanne Giorgio, Sabrina Pricl, Benjamin Guillet, Ling Peng

Chemical Communications 56:301-304 (2020)10.1039/c9cc07750b

Surface Charge of Supramolecular Nanosystems for In Vivo Biodistribution: A MicroSPECT/CT Imaging Study

Ling Ding, Zhenbin Lyu, Beatrice Louis, Aura Tintaru, Erik Laurini, Domenico Marson, Mengjie Zhang, Wanxuan Shao, Yifan Jiang, Ahlem Bouhlel, Laure Balasse, Philippe Garrigue, Eric Mas, Suzanne Giorgio, Juan Iovanna, Yuanyu Huang, Sabrina Pricl, Benjamin Guillet, Ling Peng

Small 16:301-304 (2020)10.1002/smll.202003290

Chemical Evolution of Pt–Zn Nanoalloys Dressed in Oleylamine

Alter Zakhtser, Ahmed Naitabdi, Rabah Benbalagh, François Rochet, Caroline Salzemann, Christophe Petit, Suzanne Giorgio

ACS Nano (2020)10.1021/acsnano.0c03366

2019

Efficient and innocuous delivery of small interfering RNA to microglia using an amphiphilic dendrimer nanovector

Aleksandra Ellert-Miklaszewska, Natalia Ochocka, Marta Maleszewska, Ling Ding, Erik Laurini, Yifan Jiang, Adria-Jaume Roura, Suzanne Giorgio, Bartlomiej Gielniewski, Sabrina Pricl, Ling Peng, Bozena Kaminska

Nanomedicine 14:2441-2458 (2019)10.2217/nnm-2019-0176

Oxygen Adsorption on Graphene-Encapsulated Palladium Nanoparticles Imaged by Kelvin Probe Force Microscopy

Henrik Grönbeck, Clemens Barth

Journal of Physical Chemistry C 123:24615-24625 (2019)10.1021/acs.jpcc.9b07377

Revealing Carbon Phenomena at Palladium Nanoparticles by Analyzing the Work Function

Henrik Grönbeck, Clemens Barth

Journal of Physical Chemistry C 123:4360-4370 (2019)10.1021/acs.jpcc.8b12208

2018

Carbon Precursor Structures and Graphene on Palladium Nanoparticles

Clemens Barth

Journal of Physical Chemistry C 122:522-529 (2018)10.1021/acs.jpcc.7b09885

A Dual Targeting Dendrimer-Mediated siRNA Delivery System for Effective Gene Silencing in Cancer Therapy

Yiwen Dong, Tianzhu Yu, Ling Ding, Erik Laurini, Yuanyu Huang, Mengjie Zhang, Yuhua Weng, Shuting Lin, Peng Chen, Domenico Marson, Yifan Jiang, Suzanne Giorgio, Sabrina Pricl, Xiaoxuan Liu, Palma Rocchi, Ling Peng

Journal of the American Chemical Society 140:16264-16274 (2018)10.1021/jacs.8b10021

Self-assembling supramolecular dendrimer nanosystem for PET imaging of tumors

Philippe Garrigue, Jingjie Tang, Ling Ding, Ahlem Bouhlel, Aura Tintaru, Erik Laurini, Yuanyuan Huang, Zhenbin Lyu, Mengjie Zhang, Samantha Fernandez, Laure Balasse, Wenjun Lan, Eric Mas, Domenico Marson, Yuhuang Weng, Xiaoxuan Liu, Suzanne Giorgio, Juan Iovanna, Sabrina Pricl, Benjamin Guillet, Ling Peng

Proceedings of the National Academy of Sciences of the United States of America 115:11454-11459 (2018)10.1073/pnas.1812938115

Stability of Ultrathin Ceria Films on Pt(111) Exposed to Air and Treated in Redox Cycles

Gabriele Gasperi, Paola Luches, Clemens Barth

Journal of Physical Chemistry C 122:25954-25963 (2018)10.1021/acs.jpcc.8b07231

Blocking Stemness and Metastatic Properties of Ovarian Cancer Cells by Targeting p70S6K with Dendrimer Nanovector-Based siRNA Delivery

Jing Ma, Shashwati Kala, Susan Yung, Tak Mao Chan, Yu Cao, Yifan Jiang, Xiaoxuan Liu, Suzanne Giorgio, Ling Peng, Alice Wong

Molecular Therapy 26:70-83 (2018)10.1016/j.ymthe.2017.11.006

2017

Monitoring in situ the colloidal synthesis of AuRh/TiO 2 selective-hydrogenation nanocatalysts

Zere Konuspayeva, Gilles Berhault, Pavel Afanasiev, Thanh-Son Nguyen, Suzanne Giorgio, Laurent Piccolo

Journal of Materials Chemistry A 5:17360-17367 (2017)10.1039/c7ta03965d

Surface Stabilizes Ceria in Unexpected Stoichiometry

Reinhard Olbrich, Gustavo E Murgida, Valeria Ferrari, Clemens Barth, Ana M Llois, Michael Reichling, M Veronica Ganduglia-Pirovano

Journal of Physical Chemistry C 121:6844-6851 (2017)10.1021/acs.jpcc.7b00956

CO Chemisorption on Ultrathin MgO-Supported Palladium Nanoparticles

Aimeric Ouvrard, Ahmed Ghalgaoui, Carine Michel, Clemens Barth, Jijin Wang, Serge Carrez, Wanquan Zheng, Claude R. Henry, Bernard Bourguignon

Journal of Physical Chemistry C 121:5551-5564 (2017)10.1021/acs.jpcc.6b10595

2016

Advances in the Development of a 10-kA Class REBCO Cable for the EuCARD2 Demonstrator Magnet

A. Badel, A. Ballarino, C. Barth, L. Bottura, M. M. J. Dhalle, J. Fleiter, W. Goldacker, J. Himbele, A. Kario, L. Rossi, A. Rutt, C. Scheuerlein, C. Senatore, P. Tixador, A. Usoskin, Y. Yang

IEEE Transactions on Applied Superconductivity 26:4803908 (2016)10.1109/TASC.2016.2548938

Antibacterial activities of fluorescent nano assembled triphenylamine phosphonium ionic liquids

Frédéric Brunel, Christelle Lautard, Frédéric Garzino, Suzanne Giorgio, Jean M. Raimundo, Jean M. Bolla, Michel Camplo

Bioorganic and Medicinal Chemistry Letters 26:3770-3773 (2016)10.1016/j.bmcl.2016.05.055

Mastering Dendrimer Self-Assembly for Efficient siRNA Delivery: From Conceptual Design to In Vivo Efficient Gene Silencing

Chao Chen, Paola Posocco, Xiaoxuan Liu, Qiang Cheng, Erik Laurini, Jiehua Zhou, Cheng Liu, Yang Wang, Jingjie Tang, Valentina Dal Col, Tianzhu Yu, Suzanne Giorgio, Maurizio Fermeglia, Fanqi Qu, Zicai Liang, John J. Rossi, Minghua Liu, Palma Rocchi, Sabrina Pricl, Ling Peng

Small 12:3667-3676 (2016)10.1002/smll.201503866

Core-shell Pd-Pt nanocubes for the CO oxidation

Astrid de Clercq, Olivier Margeat, Georges Sitja, Claude R. Henry, Suzanne Giorgio

Journal of Catalysis 336:33-40 (2016)10.1016/j.jcat.2016.01.005

Pd surface and Pt subsurface segregation in Pt 1− c Pd c nanoalloys

Astrid de Clercq, S. Giorgio, C. Mottet

Journal of Physics: Condensed Matter 28:064006 (2016)10.1088/0953-8984/28/6/064006

Mix and Match: Coassembly of Amphiphilic Dendrimers and Phospholipids Creates Robust, Modular, and Controllable Interfaces

Samuel Hinman, Charles Ruiz, Yu Cao, Meghann Ma, Jingjie Tang, Erik Laurini, Paola Posocco, Suzanne Giorgio, Sabrina Pricl, Ling Peng, Quan Cheng

ACS Applied Materials & Interfaces 9:1029-1035 (2016)10.1021/acsami.6b11556

Charging C-60 islands with the AFM tip

Brice Hoff, Claude R. Henry, Clemens Barth

Nanoscale 8:411-419 (2016)10.1039/c5nr04541j

A Fluorinated Bola-Amphiphilic Dendrimer for On-Demand Delivery of siRNA, via Specific Response to Reactive Oxygen Species

Xiaoxuan Liu, Yang Wang, Chao Chen, Aura Tintaru, Yu Cao, Juan Liu, Fabio Ziarelli, Jingjie Tang, Hongbo Guo, Roseline Rosas, Suzanne Giorgio, Laurence Charles, Palma Rocchi, Ling Peng

Advanced Functional Materials 26:8594-8603 (2016)10.1002/adfm.201604192

Financement

Ingénierie moléculaire et matériaux fonctionnels Sources et sondes ponctuelles 2

Coordinator: Clemens Barth, partners: Michael Reichling (Universität Osnabrück, Germany) and Henrik Grönbeck (Chalmers University, Sweden)
CINaM group: C. Barth, B. Chatelain, C. Laffon, P. Parent, G. Arthaud
Topic: we study reactivity related phenomena at single metal NPs with the help of KPFM by measuring changes of the NP’s WF. For more information, see the homepage of the project.

 

Coordinator: David Martrou (CEMES, France), partner and responsible for the CINaM: Clemens Barth, other partners: Adam Foster (Aalto University, Finland)
CINaM group: C. Barth, B. Chatelain, L. Masson, L. Santinacci, G. Arthaud
Topic: the project deals with the charge manipulation of metal nanoparticles (NPs) supported on thin insulating films. The AFM tip is used to inject charges in a controlled manner into a single NP. For more information, see the project pages.

Facilities

The group possesses an ultra-high vacuum (UHV) system, with a STM/nc-AFM and a LEED optics as the main instruments. The following components are available at the UHV chamber:

  • Room temperature AFM/STM (Scienta Omicron)
    imaging modes: STM, contact AFM, noncontact AFM, KPFM
  • Low energy electron diffraction (LEED) optics (SPALEED, Scienta Omicron)
  • Evaporators for molecules and metals (Pd, Au, Mg, Ce, etc.)
  • UHV oven allowing annealing samples by irradiation at max. 1040 K
  • Tools for thin film preparation (sputter gun)
  • Tools for reactivity experiments (gas inlet system)

 

Nanoparticules, oxides et scanning probe microscopy 3
(left) drawing of most important tools attached to the UHV system, (right) a photo of the UHV system

Collaborations

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