Localized Phenomena and Microfluidic

Introduction

AFM probe with a hanging glass fiber, built from a watch quartz tuning fork. The fiber diameter is 5 microns. We build such probes to investigate liquid liquid interfaces at local scale. (electron microscopy)

Publications

2024

Rapid Polymorphic Screening using Sessile Microdroplets: Competitive Nucleation of Mannitol Polymorphs

Ruel Cedeno, Romain Grossier, Nadine Candoni, Stéphane Veesler

CrystEngComm 26:5235-5240 (2024)10.1039/d4ce00648h

2023

Coaxial ion source: Pressure dependence of gas flow and field ion emission

D. Bedrane, A. Houël, A. Delobbe, M. Lagaize, Philippe Dumas, S. Veesler, E. Salançon

Journal of Vacuum Science & Technology B, Nanotechnology and Microelectronics 41 (2023)10.1116/6.0002795

Exploring the World of Membrane Proteins: Techniques and Methods for Understanding Structure, Function, and Dynamics

Imad Boulos, Joy Jabbour, Serena Khoury, Nehme Mikhael, Victoria Tishkova, Nadine Candoni, Hilda E Ghadieh, Stéphane Veesler, Youssef Bassim, Sami Azar, Frédéric Harb

Molecules 28:7176 (2023)10.3390/molecules28207176

CNT effective interfacial energy and pre-exponential kinetic factor from measured NaCl crystal nucleation time distributions in contracting microdroplets

Ruel Cedeno, Romain Grossier, Nadine Candoni, Nicolas Levernier, Adrian Flood, Stéphane Veesler

The Journal of Chemical Physics 158:194705 (2023)10.1063/5.0143704

Microdroplet Approach for Measuring Aqueous Solubility and Nucleation Kinetics of a Metastable Polymorph: The case of KDP Phase IV

Ruel Cedeno, Romain Grossier, Nadine Candoni, Stéphane Veesler

Crystal Growth & Design 23:9052-9057 (2023)10.1021/acs.cgd.3c01086

Modular microfluidic platform for solubility measurement, nucleation statistics and polymorph screening of active pharmaceutical ingredients: Irbesartan, Rimonabant, Aripiprazole and Sulfathiazole

Mathilde Lambert, Romain Grossier, Mehdi Lagaize, Thirou Bactivelane, Vasile Heresanu, Benoît Robert, Nadine Candoni, Stéphane Veesler

Journal of Crystal Growth 616:127252 (2023)

New Lidocaine-Based Pharmaceutical Cocrystals: Preparation, Characterization, and Influence of the Racemic vs. Enantiopure Coformer on the Physico-Chemical Properties

Panpan Ma, Balthazar Toussaint, Enrica Angela Roberti, Noémie Scornet, Axel Santos Silva, Luis Castillo Henríquez, Monique Cadasse, Philippe Négrier, Stéphane Massip, Hanh Dufat, Karim Hammad, Cecilia Baraldi, Maria Cristina Gamberini, Cyrille Richard, Stéphane Veesler, Philippe Espeau, Tu Lee, Yohann Corvis

Pharmaceutics 15:1102 (2023)10.3390/pharmaceutics15041102

2022

Evaporation Dynamics of Sessile Saline Microdroplets in Oil

Ruel Cedeno, Romain Grossier, Victoria Tishkova, Nadine Candoni, Adrian E. Flood, Stéphane Veesler

Langmuir 38:9686-9696 (2022)10.1021/acs.langmuir.2c01269

Nucleation in Sessile Saline Microdroplets: Induction Time Measurement via Deliquescence-Recrystallization Cycling

Ruel Cedeno, Romain A Grossier, Mehdi Lagaize, D. Nerini, Nadine Candoni, A. E. Flood, Stéphane Veesler

Faraday Discussions 183-197 (2022)10.1039/D1FD00090J

Bright sources under the projection microscope: using an insulating crystal on a conductor as electron source

L Lapena, D Bedrane, A Degiovanni, E. Salançon

European Physical Journal: Applied Physics (2022)

Low-macroscopic field emission structure: Using the shape of the conductor to identify a local difference in electric potential

L Lapena, A Degiovanni, V Tishkova, E. Salançon

Journal of Vacuum Science and Technology (2022)

2021

First microwave tomography approach towards a truly noninvasive, pain-free and wearable blood glucose monitoring device

Asma Bakkali, Clément Buisson, Lourdes Mounien, Jean François Landrier, Victoria Tishkova, Pierre Sabouroux

Progress In Electromagnetics Research M 102:193-206 (2021)10.2528/PIERM21032803

Impaired adhesion of neutrophils expressing Slc44a2/HNA-3b to VWF protects against NETosis under venous shear rates

Gaïa Zirka, Philippe Robert, Julia Tilburg, Victoria Tishkova, Chrissta Maracle, Paulette Legendre, Bart van Vlijmen, Marie-Christine Alessi, Peter Lenting, Pierre-Emmanuel Morange, Grace Thomas

Blood 137:2256-2266 (2021)10.1182/blood.2020008345

2020

Electrical molecular switch addressed by chemical stimuli

Hassib Audi, Yannick Viero, N Alwhaibi, Zhongrui Chen, Maksym Iazykov, Arnaud Heynderickx, Fan Xiao, David Guérin, Christophe Krzeminski, Iain Mark M Grace, Colin J Lambert, Olivier Siri, Dominique Vuillaume, Stéphane Lenfant, H.R. Klein

Nanoscale 12:10127-10139 (2020)10.1039/D0NR02461A

Microfluidic device to study flow-free chemotaxis of swimming cells

Nicolas Garcia-Seyda, Laurene Aoun, Victoria Tishkova, Valentine Seveau, Martine Biarnes-Pelicot, Marc Bajenoff, Marie-Pierre Valignat, Olivier Theodoly

Lab on a Chip 20:1639-1647 (2020)10.1039/d0lc00045k

Microfluidics platform for polymorph screening directly from powder

Guillem Peybernès, Romain Grossier, Frédéric Villard, Philippe Letellier, Nadine Candoni, Stéphane Veesler

Crystal Growth & Design 20:3882-3887 (2020)

A microfluidic method generating monodispersed microparticles with controllable sizes and mechanical properties

Cheng Zhang, Romain A Grossier, Leda Lacaria, Felix Rico, Nadine A Candoni, Stéphane A Veesler

Chemical Engineering Science 211:115322 (2020)10.1016/j.ces.2019.115322

2019

Advances in the Use of Microfluidics to Study Crystallization Fundamentals

Nadine A Candoni, Romain Grossier, Mehdi Lagaize, Stéphane Veesler

Annual Review of Chemical and Biomolecular Engineering 10:59-83 (2019)10.1146/annurev-chembioeng-060718-030312

Thermodynamic properties of mixed-layer illite-smectite by calorimetric methods: Acquisition of the enthalpies of mixing of illite and smectite layers

Hélène Gailhanou, Philippe Blanc, J. Rogez, J. Olives, G. Mikaelian, H. Kawaji, V. Montouillout, Jean-Marc Greneche, P. Vieillard, E.C. Gaucher, C.I. I Fialips, B. Madé

Journal of Chemical Thermodynamics 138:78-97 (2019)10.1016/j.jct.2019.06.004

A low-energy electron point-source projection microscope not using a sharp metal tip performs well in long-range imaging

E. Salançon, Alain Degiovanni, Laurent Lapena, Mehdi Lagaize, Roger Morin

Ultramicroscopy (2019)10.1016/j.ultramic.2019.02.022

From measuring electron charge to exploring particle-wave duality: A new didactic experimental approach

E. Salançon, Alain Degiovanni, Laurent Lapena, Roger Morin

American Journal of Physics 87:194-199 (2019)10.1119/1.5086392

Preparing a celadonite electron source and estimating its brightness

E. Salançon, Alain Jean Degiovanni, Laurent Lapena, Roger Morin

Journal of visualized experiments : JoVE 153 (2019)10.3791/59513

Multiscale Experimental Study and Modeling of l -Glutamic acid Crystallization: Emphasis on a Kinetic Explanation of the Ostwald Rule of Stages

Yousra Tahri, Emilie Gagnière, Elodie Chabanon, Tijani Bounahmidi, Zdeněk Kožíšek, Nadine Candoni, Stéphane Veesler, Moussa Boukerche, Denis Mangin

Crystal Growth & Design 19:3329-337 (2019)10.1021/acs.cgd.9b00217

2018

Microfluidics set-up rapidly measures solubility directly from powder

Guillem Peybernès, Romain A Grossier, Frédéric Villard, Philippe Letellier, Mehdi Lagaize, Nadine A Candoni, Stéphane Veesler

Organic Process Research and Development 22:1856-1860 (2018)10.1021/acs.oprd.8b00300

High spatial resolution detection of low-energy electrons using an event-counting method, application to point projection microscopy

Evelyne Salançon, Alain Degiovanni, Laurent Lapena, Roger Morin

Review of Scientific Instruments 89 (2018)10.1063/1.5020255