Département IMMF

Molecular Engineering and Functional Materials

Leader: Olivier Margeat


The IMMF research activities are at the crossroad of chemistry-physics-biology and focus mainly on the synthesis, physicochemical characterization and properties of organic, inorganic and / or hybrid molecular structures for energy, health, environment, information and communication.

These themes are structured in three main research axes that are molecular materials for photonics, molecular materials for electronics and nanomedicine with a global multidisciplinary approach (syntheses - development of nanostructured materials - characterizations), leading to the development of devices whose properties fulfill the major societal concerns.

The IMMF department has a strong knowledge and has developed a solid expertise in molecular and supramolecular chemistry that enables it to synthesize and characterize nanostructures based in particular on pi-conjugated aromatic and heteroaromatic molecules, amphiphilic, glycosidic and chiral molecules.

In this context, the molecular engineering of several original families of chromophores has been developed responding to scientific and technological issues at the forefront of current concerns.

The department is also involved in the synthesis of inorganic or hybrid nanoparticles for applications in the energy field, or organic nanoparticles and dendrimers for applications in personalized medicine and care.

A particular effort is also made to deposit, growth, self-organization of nanostructures in solution and toward the functionalization of substrates for the development of functional materials.

Équipe Fages



Exploring Charge Transport in High‐Temperature Polymorphism of ITIC Derivatives in Simple Processed Unipolar Bottom Contact Organic Field‐Effect Transistor

Yatzil Alejandra Avalos Quiroz, Tomoyuki Koganezawa, Pavlo Perkhun, Elena Barulina, Carmen Ruiz Herrero, Jörg Ackermann, Noriyuki Yoshimoto, Christine Videlot-Ackermann

Advanced Electronic Materials 2100743 (2022)10.1002/aelm.202100743

Thermostable ionizable lipid-like nanoparticle (iLAND) for RNAi treatment of hyperlipidemia

Bo Hu, Bo Li, Kun Li, Yuanyuan Liu, Chunhui Li, Lulu Zheng, Mengjie Zhang, Tongren Yang, Shuai Guo, Xiyu Dong, Tian Zhang, Qing Liu, Abid Hussain, Yuhua Weng, Ling Peng, Yongxiang Zhao, Xing-Jie Liang, Yuanyu Huang

Science Advances 8 (2022)10.1126/sciadv.abm1418

A biodegradable amphiphilic poly(aminoester) dendrimer for safe and effective siRNA delivery

Chi Ma, Dandan Zhu, Wenyi Lin, Ying Li, Yuanzheng Huang, Huiling Zhu, Mengyun Ye, Yang Wang, Ling Peng, Xiaoxuan Liu

Chemical Communications (2022)10.1039/D1CC06655B

NIR-to-NIR two-photon bio-imaging using very bright tailored amino-heptamethines dyes

Simon Pascal, San-Hui Chi, Alexei Grichine, Veronique Martel-Frachet, Joseph Perry, Olivier Maury, Chantal Andraud

Dyes and Pigments 110369 (2022)10.1016/j.dyepig.2022.110369

Highly emissive layers based on organic/inorganic nanohybrids using Aggregation Induced Emission effect

Jonathan Phelipot, Nicolas Ledos, Thomas Dombray, Matthew Duffy, Mathieu Denis, Ting Wang, Yahia Didane, Meriem Gaceur, Qinye Bao, Xianjie Liu, Mats Fahlman, Pietro Delugas, Alessandro Mattoni, Denis Tondelier, Bernard Geffroy, Pierre-Antoine Bouit, Olivier Margeat, Jörg Ackermann, Muriel Hissler

Advanced Materials Technologies 7:2100876 (2022)10.1002/admt.202100876

Synthesis and Electron Accepting Properties of Two Di(benz[f]indenone)-Fused Tetraazaanthracene Isomers

Bruno Salgues, Rudraditya Sarkar, Muhammad Fajri, Yatzil Avalos-Quiroz, Anne-Doriane Manick, Michel Giorgi, Nicolas Vanthuyne, Yannick Carissan, Christine Videlot-Ackermann, Jörg Ackermann, Gabriel Canard, Jean-Luc Parrain, Boris Le Guennic, Denis Jacquemin, Muriel Amatore, Laurent Commeiras, Elena Zaborova, Fréderic Fagès

Journal of Organic Chemistry 87:3276-3285 (2022)10.1021/acs.joc.1c02942


Organic-Inorganic doped Nickel Oxide Nanocrystals for Hole Transport Layers in Inverted Polymer Solar Cells with Color Tuning

Riva Alkarsifi, Yatzil Alejandra Avalos-Quiroz, Pavlo Perkhun, Xianjie Liu, Mats Fahlman, Anil Kumar Bharwal, Carmen M. Ruiz, David Duché, Jean-Jacques Simon, Christine Videlot-Ackermann, Olivier Margeat, Jörg Ackermann

Materials Chemistry Frontiers (2021)

Non-Fullerene Acceptors with an Extended Pi-Conjugated Core: Third Components in Ternary Blends for High-Efficiency, Post Treatment-Free, Organic Solar Cells

Yatzil Alejandra Avalos Quiroz, Olivier Bardagot, Yann Kervella, Cyril Aumaître, Lydia Cabau, Agnès Rivaton, Olivier Margeat, Christine Videlot-Ackermann, Uyxing Vongsaysy, Jörg Ackermann, Renaud Demadrille

ChemSusChem 14:3502-3510 (2021)10.1002/cssc.202101005

Azacalixphyrins as an Innovative Alternative for the Free-Radical Photopolymerization under Visible and NIR Irradiation without the Need of Co-Initiators

Louise Breloy, Rana Mhanna, Jean-Pierre Malval, V. Brezova, Denis Jacquemin, Simon Pascal, Olivier Siri, Davy-Louis Versace

Chemical Communications 57:8973-8976 (2021)10.1039/D1CC03607F

Theoretical insight on PTB7:PC 71 BM, PTB7-th:PC 71 BM and Si-PCPDTBT:PC 71 BM interactions governing blend nanoscale morphology for efficient solar cells

Claudia Caddeo, Alessio Filippetti, Andrea Bosin, Christine Videlot-Ackermann, Jörg Ackermann, Alessandro Mattoni

Nano Energy (2021)

Significance Of Nuclear Quantum Effects In Hydrogen Bonded Molecular Chains

Aleš Cahlík, Jack Hellerstedt, Jesús Mendieta-Moreno, Martin Švec, Vijai Santhini, Simon Pascal, Diego Soler-Polo, Sigurdur Erlingsson, Karel Výborný, Pingo Mutombo, Ondrej Marsalek, Olivier Siri, Pavel Jelínek

ACS Nano (2021)10.1021/acsnano.1c02572

Synthesis and use of an amphiphilic dendrimer for siRNA delivery into primary immune cells

Jiaxuan Chen, Aleksandra Ellert-Miklaszewska, Stefano Garofalo, Arindam Dey, Jingjie Tang, Yifan Jiang, Flora Clément, Patrice Marche, Xiaoxuan Liu, Bozena Kaminska, Angela Santoni, Cristina Limatola, John Rossi, Jiehua Zhou, Ling Peng

Nature Protocols (2021)10.1038/s41596-020-00418-9

Modified Indulines: From Dyestuffs to in vivo Theranostic Agents

Zhongrui Chen, Simon Pascal, Morgane Daurat, Laure Lichon, Christophe Nguyen, Anastasia Godefroy, Denis Durand, Lamiaa Ali, Nadir Bettache, Magali Gary-Bobo, Philippe Arnoux, Jean-François Longevial, Anthony Aléo, Gabriel Marchand, Denis Jacquemin, Olivier Siri

ACS Applied Materials & Interfaces (2021)10.1021/acsami.1c05933

A self-assembling prodrug nanosystem to enhance metabolic stability and anticancer activity of gemcitabine

Mei Cong, Guangling Xu, Shaoyou Yang, Jing Zhang, Wenzheng Zhang, Dinesh Dhumal, Erik Laurini, Kaiyue Zhang, Yi Xia, Sabrina Pricl, Ling Peng, Weidong Zhao

Chinese Chemical Letters (2021)10.1016/j.cclet.2021.11.083

Reversible pH‐Controlled Catenation of a Benzobisimidazole‐based Tetranuclear Rectangle

Maksym Dekhtiarenko, Simon Pascal, Mourad Elhabiri, Valérie Mazan, David Canevet, Magali Allain, Vincent Carré, Frédéric Aubriet, Zoia Voitenko, Marc Sallé, Olivier Siri, Sébastien Goeb

Chemistry - A European Journal 27:15922-15927 (2021)10.1002/chem.202103039

Electronic and magnetic properties of metal–organic polymers with 4d and 5d-transition metal ions

Hassan Denawi, Mathieu Abel, Olivier Siri, Roland Hayn

Journal of Magnetism and Magnetic Materials 537:168183 (2021)10.1016/j.jmmm.2021.168183

An ionizable supramolecular dendrimer nanosystem for effective siRNA delivery with a favorable safety profile

Dinesh Dhumal, Wenjun Lan, Ling Ding, Yifan Jiang, Zhenbin Lyu, Erik Laurini, Domenico Marson, Aura Tintaru, Nelson Dusetti, Suzanne Giorgio, Juan Lucio Iovanna, Sabrina Pricl, Ling Peng

Nano Research (2021)10.1007/s12274-020-3216-8

NUPR1 inhibitor ZZW-115 induces ferroptosis in a mitochondria-dependent manner

Can Huang, Patricia Santofimia-Castaño, Xi Liu, Yi Xia, Ling Peng, Célia Gotorbe, Jose Luis Neira, Daolin Tang, Jacques Pouyssegur, Juan Iovanna

Cell Death Discovery 7:269 (2021)10.1038/s41420-021-00662-2

Functionalized porphyrins from meso-poly-halogeno-alkyl-dipyrromethanes: synthesis and characterization

Paul-Gabriel Julliard, Simon Pascal, Olivier Siri, Diego Cortés-Arriagada, Luis Sanhueza, G. Canard

Comptes Rendus. Chimie 24:1-19 (2021)10.5802/crchim.97

Dendrimeric Nanosystem Consistently Circumvents Heterogeneous Drug Response and Resistance in Pancreatic Cancer

Juan Liu, Chao Chen, Tuo Wei, Odile Gayet, Céline Loncle, Laurence Borge, Nelson Dusetti, Xiaowei Ma, Domenico Marson, Erik Laurini, Sabrina Pricl, Zhongwei Gu, Juan Iovanna, Ling Peng, Xing‐jie Liang

Energy Exploration and Exploitation 1:21-34 (2021)10.1002/EXP.20210003

The Quinonoid Zwitterion Interlayer for the Improvement of Charge Carrier Mobility in Organic Field-Effect Transistors

Adam Luczak, Angélina Ruiz, Simon Pascal, Adrian Adamski, Jarosław Jung, Beata Luszczynska, Olivier Siri

Polymers 13:1567 (2021)10.3390/polym13101567

Near-infrared dyes for two-photon absorption in the short-wavelength infrared: strategies towards optical power limiting

Simon Pascal, Sylvain David, Chantal Andraud, Olivier Maury

Chemical Society Reviews (2021)10.1039/D0CS01221A

High‐Efficiency Digital Inkjet‐Printed Non‐Fullerene Polymer Blends Using Non‐Halogenated Solvents

Pavlo Perkhun, Wolfgang Köntges, Florent Pourcin, Daniel Esteoulle, Elena Barulina, Noriyuki Yoshimoto, Pascal Pierron, Olivier Margeat, Christine Videlot-Ackermann, Anil Kumar Bharwal, David Duché, Carmen Ruiz Herrero, Cedric Gonzales, Antonio Guerrero, Juan Bisquert, Rasmus Schröder, Martin Pfannmöller, Sadok Ben Dkhil, Jean-Jacques Simon, Jörg Ackermann

Advanced Energy and Sustainability Research 2000086 (2021)10.1002/aesr.202000086

Design of Inhibitors of the Intrinsically Disordered Protein NUPR1: Balance between Drug Affinity and Target Function

Bruno Rizzuti, Wenjun Lan, Patricia Santofimia-Castaño, Zhengwei Zhou, Adrián Velázquez-Campoy, Olga Abián, Ling Peng, José Neira, Yi Xia, Juan Iovanna

Biomolecules 11:1453 (2021)10.3390/biom11101453


Direct correlation of nanoscale morphology and device performance to study photocurrent generation in donor enriched phases of polymer solar cells

Sadok Ben Dkhil, Pavlo Perkhun, Chieh Luo, David Müller, Riva Alkarsifi, Elena Barulina, Yatzil Alejandra Avalos-Quiroz, Olivier Margeat, Stephan Thierry Dubas, Tomoyuki Koganezawa, Daiki Kuzuhara, Noriyuki Yoshimoto, Claudia Caddeo, Alessandro Mattoni, Birger Zimmermann, Uli Würfel, Martin Pfannmöller, Sara Bals, Jörg Ackermann, Christine Videlot-Ackermann

ACS Applied Materials & Interfaces (2020)10.1021/acsami.0c05884

Robust transparent conducting electrode based on silver nanowire coating on polyelectrolytes multilayers

Jedsada Chavalitkul, Olivier Margeat, Jörg Ackermann, Stephan Dubas

Thin Solid Films 711:138272 (2020)10.1016/j.tsf.2020.138272

Visualizing morphological principles for efficient photocurrent generation in organic non-fullerene acceptor blends

Wolfgang Köntges, Pavlo Perkhun, Jochen Kammerer, Riva Alkarsifi, Uli Würfel, Olivier Margeat, Christine Videlot-Ackermann, Jean-Jacques Simon, Rasmus Schröder, Jörg Ackermann, Martin Pfannmöller

Energy & Environmental Science 13 (2020)10.1039/c9ee03535d

Impacts of Ion‐Pairing Effects on Linear and Nonlinear Photophysical Properties of Polymethines Dyes

Simon Pascal, San-Hui Chi, Joseph Perry, Chantal Andraud, Olivier Maury, S.-H Chi

ChemPhysChem (2020)10.1002/cphc.202000731

Small Panchromatic and NIR Absorbers from Quinoid Zwitterions

Angélina Torres Ruiz, Manon Bousquet, Simon Pascal, Gabriel Canard, Valérie Mazan, Mourad Elhabiri, Denis Jacquemin, Olivier Siri

Organic Letters (2020)10.1021/acs.orglett.0c02926

Long-standing Optically-excited Magnetic States in ZnO Nanoparticles

Adrien Savoyant, Clément Sebastiao, Olivier Margeat

physica status solidi (RRL) - Rapid Research Letters (2020)10.1002/pssr.202000176


  • 06/02/2019: Elena Barulina & Jonathan Phelipot

  • 13/02/2019: Yatzil Avalos & Bruno Salgues

  • 20/02/2019: Jiaxuan Chen & Pavlo Perkhun

  • 27/02/2019: Angélina Torres Ruiz & Frédéric Brunel

  • 06/03/2019: Sanjana Auditto & Wenjun Lan

  • 13/03/2019: Riva Alkarsifi & Dinesh Dumal

  • 20/03/2019: Zhenbin Lyu & Manon Catherin

  • 27/03/2019: Yifan Jiang & Ling Ding

  • 10/04/2019: Yi-Wen Yao & Yatzil Avalos

  • 17/04/2019: Elena Barulina & Bruno Salgues

  • 24/04/2019: Jiaxuan Chen

  • 15/05/2019: Angélina Torres Ruiz

  • 22/05/2019: Sanjana Auditto & Jonathan Phelipot

  • 29/05/2019: Manon Catherin & Dinesh Dumal

  • 26/06/2019: Riva Alkarsifi & Pavlo Perkhun

  • 03/07/2019: Serena Carrara & Frédéric Brunel

  • 10/07/2019: Ling Ding & Yi-Wen Yao

  • 17/07/2019: Yifan Jiang & Zhenbin Lyu


Équipe Ackermann 1 Sources et sondes ponctuelles 2 Physique et nano-micro Ingénierie pour le Vivant 1 Équipe Peng Équipe Peng 1

  • ANR contracts

  • 1 Doc2AMU fellowship

  • 1 collaboration contract with Dracula Technologie company

  • 1 AMidex project

  • 1 "Ligue contre le Cancer" labeled team

  • 2 Horizon 2020 contracts