Département IMMF

Ingénierie Moléculaire et Matériaux Fonctionnels

Responsable : Olivier Margeat

Présentation

Les activités de recherche du département IMMF se situent à l’interface chimie-physique-biologie et portent sur la synthèse, les caractérisations physico-chimiques et les études des propriétés de structures moléculaires organiques, inorganiques et/ou hybrides.

Ces activités sont structurées autour de trois thématiques :

 


Nanomédecine
Biomatériaux

 

  • Vectorisation



 

  • Bioimagerie / Diagnostique



 

  • Thérapie





 


Structures conjuguées
singulières

 

  • Ingénierie de chromophores et fluorophores



 

  • Interrupteurs moléculaires

 

  • Chimie supramoléculaire


 


Surfaces, couches minces
& dispositifs

 

  • Assemblage sur surface




 

  • Revêtements fonctionnels


 

  • Dispositifs optoélectroniques

 

Publications

2024

Between hope and reality: treatment of genetic diseases through nucleic acid-based drugs

Virginie Baylot, Thi Khanh Le, David Taïeb, Palma Rocchi, Laurence Colleaux

Communications Biology 7:489 (2024)10.1038/s42003-024-06121-9

Controlled Reactivity of Viologens in Alkaline Solutions Via Cucurbit[7]uril Complexation

Axel Bossavit, Valérie Monnier, Didier Siri, Gabriel Canard, Didier Gigmes, David Bardelang, Anthony Kermagoret

European Journal of Organic Chemistry 27:e202400404 (2024)10.1002/ejoc.202400404

Correlation between materials and band‐selective detection in organic photodetectors based on bulk heterojunction

Quentin Eynaud, Anass Khodr, Mohamed El Amine Kramdi, Gilles Quéléver, Olivier Margeat, Jörg Ackermann, Christine Videlot-Ackermann

Journal of Applied Polymer Science (2024)10.1002/app.55481

Toward Air Stability of Efficient Filter‐Free Band‐Selective Organic Photodetectors Based on Bulk Heterojunction: Avoiding Environmental Degradation with Atomic Layer Deposition Encapsulation

Quentin Eynaud, Mohamed El Amine Kramdi, Vyshnav Kannampalli, Tomoyuki Koganezawa, Noriyuki Yoshimoto, Lionel Santinacci, Jörg Ackermann, Christine Videlot-Ackermann

Advanced Energy and Sustainability Research 2300262 (2024)10.1002/aesr.202300262

Ternary Polymer Solar Cells: Impact of Non-Fullerene Acceptors on Optical and Morphological Properties

Quentin Eynaud, Tomoyuki Koganezawa, Hidehiro Sekimoto, Mohamed El Amine Kramdi, Gilles Quéléver, Olivier Margeat, Jörg Ackermann, Noriyuki Yoshimoto, Christine Videlot-Ackermann

Electronics 13:1752 (2024)10.3390/electronics13091752

Tuning the Electronic Properties of Bridged Dithienyl‐, Difuryl‐, Dipyrrolyl‐Vinylene as Precursors of Small‐Bandgap Conjugated Polymer.

Jordan Garo, Tommaso Nicolini, Jean-Marc Sotiropoulos, Jean‐manuel Raimundo

Chemistry - A European Journal 30:e202402461 (2024)10.1002/chem.202402461

Two-step access to bis- meso -perfluoroalkyl-corroles towards meso -perfluoroacyl-ABC-corroles

Paul-Gabriel Julliard, Simon Pascal, Olivier Siri, Michel Giorgi, Diego Cortés-Arriagada, Luis Sanhueza, Gabriel Canard

Organic & Biomolecular Chemistry (2024)10.1039/D4OB00191E

Amphiphilic Dendrimer as Potent Antibacterial against Drug-Resistant Bacteria in Mouse Models of Human Infectious Diseases

Noah King, Dinesh Dhumal, Shi Qian Lew, Shanny Hsuan Kuo, Christina Galanakou, Myung Whan Oh, Sook Yin Chong, Nian Zhang, Leo Tsz On Lee, Zvi Hayouka, Ling Peng, Gee W Lau

ACS Infectious Diseases 10:453-466 (2024)10.1021/acsinfecdis.3c00425

Development of an efficient NUPR1 inhibitor with anticancer activity

Xi Liu, Ana Jimenez-Alesanco, Zexian Li, Bruno Rizzuti, José L Neira, Matías Estaras, Ling Peng, Eduardo Chuluyan, Juan Garona, Florencia Gottardo, Adrián Velazquez-Campoy, Yi Xia, Olga Abian, Patricia Santofimia-Castaño, Juan Iovanna

Scientific Reports 14:29515 (2024)10.1038/s41598-024-79340-z

Self-assembling dendrimer nanosystems for specific fluorine magnetic resonance imaging and effective theranostic treatment of tumors

Zhenbin Lyu, Brigino Ralahy, Teodora-Adriana Perles-Barbacaru, Ling Ding, Yifan Jiang, Baoping Lian, Tom Roussel, Xi Liu, Christina Galanakou, Erik Laurini, Aura Tintaru, Suzanne Giorgio, Sabrina Pricl, Xiaoxuan Liu, Monique Bernard, Juan Iovanna, Angèle Viola, Ling Peng

Proceedings of the National Academy of Sciences of the United States of America 121:e2322403121 (2024)10.1073/pnas.2322403121

Coupled Polymethine Dyes: Six Decades of Discoveries

Benjamin Mourot, Denis Jacquemin, Olivier Siri, Simon Pascal

Chemical Record e202400183 (2024)10.1002/tcr.202400183

Feasibility of Multiple Excited-State Proton Transfer Processes in Hydroxyquinoline-containing Benzobisimidazole Dyes

Tatiana Munteanu, Dancho Yordanov, Gabriel Canard, Olivier Siri, Denis Jacquemin, Anton Georgiev, Simon Pascal

New Journal of Chemistry 48:13289-13295 (2024)10.1039/D4NJ01787K

Post-functionalization of triamino-phenazinium dyes to reach near-infrared emission

Tatiana Munteanu, Jean-François Longevial, Gabriel Canard, Denis Jacquemin, Simon Pascal, Olivier Siri

RSC Advances 14:19257-19263 (2024)10.1039/D4RA03245D

High-Order Commensurate Zwitterionic Quinonoid Phase Induces a Nanoscale Dipole Lattice on Graphene

Gaelle Nassar, Diego Cortés-Arriagada, Luis Sanhueza-Vega, Périne Landois, Matthieu Paillet, Haitham Hrich, Sylvie Contreras, Olivier Siri, Simon Pascal, Laurence Masson, Conrad Becker, Alain Ranguis, Romain Parret, Gabriel Canard, Thomas Leoni

Journal of Physical Chemistry C 128:9712-9721 (2024)10.1021/acs.jpcc.4c01695

1,2,4-triamino-5-nitrobenzene as air-stable aromatic polyamines for coordination chemistry

Simon Pascal, Elena Zaborova, Olivier Siri

Comptes Rendus. Chimie 27:1-7 (2024)10.5802/crchim.292

Statistical and Correlative Characterization of Individual Nanoparticle in Gap Plasmon Resonator Sensors

Peeranuch Poungsripong, Vyshnav Kannampalli, Lionel Santinacci, David Grosso, Dominique Chatain, David Duché, Olivier Margeat, Beniamino Sciacca

Advanced Materials Technologies 202400083 (2024)10.1002/admt.202400083

Insights into the relationship between molecular and order-dependent photostability of ITIC derivatives for the production of photochemically stable blends

Y. Quiroz Avalos, Quentin Eynaud, Pavlo Perkhun, Agnès Rivaton, Wolfgang Köntges, Rasmus R Schröder, Tomoyuki Koganezawa, Noriyuki Yoshimoto, A. Kumar Bharwal, David Duché, Carmen M M Ruiz, Olivier Margeat, Cyril Aumaitre, Renaud Demadrille, Christine Videlot-Ackermann, Jörg Ackermann

Journal of Materials Chemistry C (2024)10.1039/D3TC04614A

Insight into the Internal Structure of High-Performance Multicore Magnetic Nanoparticles Used in Cancer Thermotherapy

Tom Roussel, Daniel Ferry, Artemis Kosta, Dalila Miele, Giuseppina Sandri, Felista Tansi-Lemnyui, Frank Steiniger, Paul Southern, Quentin Pankhurst, Ling Peng, Suzanne Giorgio

ACS Materials Au (2024)

Bis‐Indeno‐Fused Tetraazaanthracene Hybrids: Straightforward Synthesis and Studies of Optical and Electronic Properties

Bruno Salgues, Rudraditya Sarkar, Nans Potier, Anne-Doriane Manick, Gabriel Canard, Jean-Luc Parrain, Michel Giorgi, Nicolas Vanthuyne, Christine Videlot-Ackermann, Jörg Ackermann, Fréderic Fagès, Boris Le Guennic, Denis Jacquemin, Muriel Amatore, Elena Zaborova, Laurent Commeiras

European Journal of Organic Chemistry e202400719 (2024)10.1002/ejoc.202400719

Designer metasurfaces via nanocube assembly at the air-water interface

Beniamino Sciacca, Muhammad L. Fajri, Nicolas Kossowski, Ibtissem Bouanane, F. Bedu, Peeranuch Poungsripong, Renato Juliano-Martins, Clement Majorel, Olivier Margeat, Judikaël Le Rouzo, Patrice Genevet

ACS Nano 18 (2024)https://pubs.acs.org/doi/10.1021/acsnano.4c06022

Self-assembled monolayers of push-pull chromophores as active layer and their applications

Junlong Wang, Virginie Gadenne, Lionel Patrone, Jean-Manuel Raimundo

Molecules 29:559 (2024)10.3390/molecules29030559

The synergistic neurovascular electro-healing of infected diabetic wounds by a multifaceted absorbable ion-conductive adhesive patch

Wenlong Wei, Jiayi Zheng, Ziru Liu, Ziqiu Li, Xiangyu Chen, Wenyue Yang, Pier-Luc Tremblay, Ling Peng, Tian Zhang

Chemical Engineering Journal 500:156387 (2024)10.1016/j.cej.2024.156387

Internal Dynamics and Modular Peripheral Binding in Stimuli‐Responsive 3 : 2 Host:Guest Complexes

Hang Yin, Roselyne Rosas, Stéphane Viel, Michel Giorgi, Valerie Monnier, Laurence Charles, Didier Siri, Didier Gigmes, Youssef Nassar, Floris Chevallier, Christophe Bucher, Ruibing Wang, Anthony Kermagoret, David Bardelang

Angewandte Chemie International Edition 63:e202315985 (2024)10.1002/anie.202315985

Electrocatalytic Properties of meso ‐ Perfluorinated Metallo Corroles for the Reduction of CO 2

Chanjuan Zhang, Paul‐gabriel Julliard, Diana Dragoe, Ally Aukauloo, Gabriel Canard

European Journal of Inorganic Chemistry 27:e202400318 (2024)10.1002/ejic.202400318

Targeting the phosphatidylglycerol lipid: An amphiphilic dendrimer as a promising antibacterial candidate

Nian Zhang, Dinesh Dhumal, Shanny Hsuan Kuo, Shi Qian Lew, Pankaj Patil, Raleb Taher, Sanika Vaidya, Christina Galanakou, Abdechakour Elkihel, Myung Whan Oh, Sook Yin Chong, Domenico Marson, Jun Zheng, Oleg Rouvinski, Williams Abolarin, Sabrina Pricl, Gee Lau, Leo Tsz On Lee, Ling Peng

Science Advances 10:eadn8117 (2024)10.1126/sciadv.adn8117

Capture and flocculation of toxic cyanobacteria by amphiphilic peptide dendrimers for mitigating harmful blooms

Heng Zheng, Pier-Luc Tremblay, Wang Chen, Qi Wang, Danni Hu, Yuanzheng Huang, Xiaoxuan Liu, Cheng-Cai Zhang, Ling Peng, Tian Zhang

Chemical Engineering Journal (2024)10.1016/j.cej.2024.151382

2023

Modular Self‐Assembling Dendrimer Nanosystems for Magnetic Resonance And Multimodality Imaging of Tumors

Ling Ding, Zhenbin Lyu, Teodora‐adriana Perles-Barbacaru, Adela Ya‐ting Huang, Baoping Lian, Yifan Jiang, Tom Roussel, Christina Galanakou, Suzanne Giorgio, Chai‐lin Kao, Xiaoxuan Liu, Juan Iovanna, Monique Bernard, Angèle Viola, Ling Peng

Advanced Materials (2023)10.1002/adma.202308262

Core–Shell Multiwalled Carbon Nanotube/Cobalt Corrole Hybrids for the Oxygen Reduction Reaction

Paul-Gabriel Julliard, Manel Hanana, Laurent Alvarez, Renaud Cornut, Bruno Jousselme, Gabriel Canard, Stéphane Campidelli

Energy & Fuels 37:684-692 (2023)10.1021/acs.energyfuels.2c03434

Star-shape non-fullerene acceptor featuring an aza-triangulene core for organic solar cells

Yann Kervella, José Maria Andrés Castán, Yatzil Alejandra Avalos-Quiroz, Anass Khodr, Quentin Eynaud, Tomoyuki Koganezawa, Noriyuki Yoshimoto, Olivier Margeat, Agnès Rivaton, Antonio Riquelme, Valid Mwatati Mwalukuku, Jacques Pécaut, Benjamin Grévin, Christine Videlot-Ackermann, Jörg Ackermann, Renaud Demadrille, Cyril Aumaître

Journal of Materials Chemistry C 11:8161-8169 (2023)10.1039/d2tc05424h

DDX5 mRNA-targeting antisense oligonucleotide as a new promising therapeutic in combating castration-resistant prostate cancer

Thi Khanh Le, Chaïma Cherif, Kenneth Omabe, Clément Paris, François Lannes, Stéphane Audebert, Emilie Baudelet, Mourad Hamimed, Dominique Barbolosi, Pascal Finetti, Cyrille Bastide, Ladan Fazli, Martin Gleave, François Bertucci, David Taïeb, Palma Rocchi

Molecular Therapy 31:471-486 (2023)10.1016/j.ymthe.2022.08.005

Financement

Équipe Ackermann 1 Sources et sondes ponctuelles 2 Physique et nano-micro Ingénierie pour le Vivant 1 Équipe Peng Équipe Peng 1

  • 5 contrats ANR

  • 1 bourse Doc2AMU

  • 1 contrat de collaboration avec la société Dracula technologie

  • 1 projet AMidex

  • 1 équipe labellisée par la Ligue contre le Cancer

  • 2 contrats Horizon 2020