Nanomédecine
Biomatériaux
- Vectorisation
- Bioimagerie / Diagnostique
- Thérapie
Structures conjuguées
singulières
- Ingénierie de chromophores et fluorophores
- Interrupteurs moléculaires
- Chimie supramoléculaire
Surfaces, couches minces
& dispositifs
- Assemblage sur surface
- Revêtements fonctionnels
- Dispositifs optoélectroniques
2026
A pH-Responsive Cu-Corrole-Based Cage That Reversibly Encapsulates Fullerene in a Shapeshifting Low-Symmetry Cavity
Anna Baidiuk, Tània Pèlachs, Paul-Gabriel Julliard, György Szalóki, Marc Vedrenne, Xavi Ribas, Maylis Orio, Alexandre Martinez, Gabriel Canard, Cédric Colomban
Journal of the American Chemical Society 148:15761-15770 (2026)10.1021/jacs.5c21440
Impact of Co‐Solvents and Additives on the Indoor Stability of Green Solvent‐Processed Organic Solar Cells
Ignacio Ballesteros García, Anass Khodr, Takeshi Watanabe, Hidehiro Sekimoto, Hasan Alkhatib, Donia Fredj, Sadok Ben Dkhil, Carmen Ruiz Herrero, Jean‐jacques Simon, Simon Desbief, Olivier Margeat, Christine Videlot-Ackermann, Judikaël Le Rouzo, Jörg Ackermann
Solar RRL 10:e70373 (2026)10.1002/solr.70373
A Zirconium Aza-BODIPY Derivative as a Near-Infrared Fluorescent/Photoacoustic Imaging Bimodal Probe
Mohamed Bendellaa, Amélie Godard, Charlotte Cave, Ghadir Kalot, Ludmilla Verrieux, Julie Pineau, Maxime Henry, Florian Chotard, Annika Sickinger, Laura Abad Galán, Véronique Josserand, Pierre Le Gendre, Christine Goze, Simon Pascal, Arnaud Fihey, Boris Le Guennic, Olivier Maury, Chantal Andraud, Benoit Busser, Ewen Bodio, Lucie Sancey
Journal of Medicinal Chemistry 69:16949-16963 (2026)10.1021/acs.jmedchem.6c00735
Substituent‐Controlled Ring Opening of 1‐Substituted Benzocyclobutenes: Electronic Structure and Diradical Character of Ortho ‐Quinodimethane Intermediates
Magali Dallegre, Imen Abid, Roselyne Rosas, Maxime Dousset, Gaëlle Chouraqui, Laurent Commeiras, Didier Siri, Didier Gigmes, Anthony Kermagoret
Chemistry - A European Journal (2026)10.1002/chem.202503431
HSP27 functional switch drives castration-resistant prostate cancer via mTOR pathway activation, highlighting promising combination therapies
Quang Hieu Duong, Thi Khanh Le, Thi Thom Tran, Stéphane Audebert, Luc Camoin, Ngan Giang Nguyen, Michael Baboudjian, Sophie Giusiano, Uyen Thi Tu Phan, Souhaila Zaghdoudi, José Adelaide, Virginie Baylot, Martin Gleave, Carmen Garrido, David Taïeb, Palma Rocchi
Journal of experimental & clinical cancer research 45:98 (2026)10.1186/s13046-026-03695-6
Self-assembling supramolecular dendrimers for biomedical applications
Abdechakour Elkihel, Jing Wu, Ling Peng
Comptes Rendus. Chimie 29:321-347 (2026)10.5802/crchim.451
Through Analysis of Thin Films Based on Small-Molecule and Polymer NFA Blends for Photovoltaic Conversion: From Neat Materials to Ternary Systems
A Kramdi, Aral Karahan, Takeshi Watanabe, Hidehiro Sekimoto, Simon Desbief, Gilles Quéléver, Olivier Margeat, Jörg Ackermann, Carmen M Ruiz, Christine Videlot-Ackermann
Physchem 6 (2026)10.3390/physchem6010012
Antioxidant lipid nanoparticles enhance mRNA stability for regeneration therapy and gene editing
Benhao Li, Mengyao Zhao, Bowei Yang, Taihua Yang, Yongling Wang, Yaxin Hu, Miao Zhang, Jiahao Ge, Xianglong Tang, Ze Zhang, Hengqing Cui, Xiaoyuan Chen, Yi Yan Yang, Ling Peng, Qianqian Ni
Nature Communications 17:7166 (2026)10.1038/s41467-026-73512-3
Fluorinated Amphiphilic Dendrimer to Improve PET Imaging of Cancer
Béatrice Louis, Tom Roussel, Twiany Cruz‐dubois, Ling Ding, Zhenbin Lyu, Erik Laurini, Jessica Ou, Laure Balasse, Adrien Chabert, Vincent Nail, Ahlem Bouhlel, Françoise Dignat‐george, Florence Gattacceca, Sabrina Pricl, Benjamin Guillet, Ling Peng, Philippe Garrigue
Small (2026)10.1002/smll.202511972
Amphiphilic poly(aminoester) dendrimers: click reaction–enabled synthesis, structure-governed self-assembly and degradation
Yonghui Ma, Junyue Zheng, Dandan Zhu, Xianhui Lin, Dan Yang, Aoxue Mei, Chi Ma, Haijuan Dong, Ling Peng, Xiaoxuan Liu
Chemical Communications 62:8657-8660 (2026)10.1039/d6cc00300a
Muribaculum intestinale negatively impacts glioma growth in mice through the toll-like receptor 2
Francesco Marrocco, Germana Cocozza, Fabrizio Antonangeli, Rizwan Khan, Giuseppe Pietropaolo, Abdechakour Elkihel, Gabriele Favaretto, Xingzi Lin, Romina Mancinelli, Ludovica Maria Busdraghi, Alice Reccagni, Gianluca Scarno, Mattia Laffranchi, Ling Peng, Valerio Iebba, Silvano Sozzani, Giuseppina D’alessandro, Cristina Limatola, Giuseppe Sciumè
Gut microbes 18 (2026)10.1080/19490976.2026.2623349
Quantitative analysis of oligonucleotide delivery into isolated mitochondria: a proof-of-concept method
Joshua Mchale, Veronica Bazzani, Abdechakour Elkihel, Jing Wu, Ling Peng, Carlo Vascotto
Biotechniques 78:1-11 (2026)10.1080/07366205.2026.2635461
Tetraazapentacene Zwitterion as Visible and Sunlight Photoinitiator for Free Radical Polymerization
Fares Mouhoubi, Elvina Barré, Anaïs Goupille, Davy‐louis Versace, Simon Pascal
ChemPhotoChem 10:e202600010 (2026)10.1002/cptc.202600010
Examination of the Aromatic vs. Coupled Polymethine Character in Dicationic and Neutral Acceptor-Donor-Acceptor Dyes
Benjamin Mourot, Carmelo Naim, Gabriel Canard, Rachel Reboh, Olivier Siri, Denis Jacquemin, Simon Pascal
Journal of Organic Chemistry (2026)10.1021/acs.joc.5c02985
Synthesis and Properties of Cross‐Shaped Donor–Acceptor Dyes: Tunable Emission From Visible to Near‐Infrared in Solution and Solid‐State
Benjamin Mourot, Gabriel Canard, Michel Giorgi, Olivier Siri, Denis Jacquemin, Simon Pascal
European Journal of Organic Chemistry (2026)10.1002/ejoc.70650
Precision chemical engineering of dendrimers for nucleic acid delivery
Qianqian Ni, Donald A Tomalia, Jing Wu, Christina Galanakou, Ling Peng
Nature Reviews Chemistry (2026)10.1038/s41570-026-00855-2
High-Efficiency Thick-Film Organic Cells for Indoor Photovoltaics Printed in Air from Non-Halogenated Solvents
Pavlo Perkhun, Anass Khodr, Yatzil Alejandra Avalos Quiroz, Aral Karahan, Hasan Alkhatib, Anil Kumar Bharwal, David Duché, Jean-Jacques Simon, Carmen M Ruiz Herrero, Takeshi Watanabe, Hidehiro Sekimoto, Noriyuki Yoshimoto, Olivier Margeat, Christine Videlot-Ackermann, Jörg Ackermann
Energies 19:1773 (2026)10.3390/en19071773
Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment
Jing Wu, Jiaxuan Chen, Abdechakour Elkihel, Wenjun Lan, Nicolas Fraunhoffer, Dandan Zhu, Baoping Lian, Christina Galanakou, Zhancun Bian, Xi Liu, Odile Gayet, Loic Moubri, Julie Aglietti Roques, Vikash Reebye, Nagy Habib, Xiaoxuan Liu, Nelson Dusetti, Juan Lucio Iovanna, Ling Peng
Advanced Science e76840 (2026)10.1002/advs.76840
2025
An antisense oligonucleotide targeting the heat‐shock protein HSPB5 as an innovative therapeutic approach in pulmonary fibrosis
Pierre‐marie Boutanquoi, Lenny Pommerolle, Lucile Dondaine, Julie Tanguy, Pierre‐simon Bellaye, Léo Biziorek, Marine Gautier-Isola, Bernard Mari, Denis Masnikov, Palma Rocchi, Pascal Finetti, Patricia Korczak, Brune Vialet, Philippe Barthelemy, Carmen Garrido, Philippe Bonniaud, Olivier Burgy, Françoise Goirand
British Journal of Pharmacology 182:2713-2729 (2025)10.1111/bph.17470
Correction: Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity
Chaïma Cherif, Dang Tan Nguyen, Clément Paris, Thi Khanh Le, Thibaud Sefiane, Nadine Carbuccia, Pascal Finetti, Max Chaffanet, Abdessamad El Kaoutari, Julien Vernerey, Ladan Fazli, Martin Gleave, Mohamed Manai, Philippe Barthélémy, Daniel Birnbaum, François Bertucci, David Taïeb, Palma Rocchi
Oncogene 44:4440-4440 (2025)10.1038/s41388-025-03614-7
Amphiphilic dendrimer-assisted delivery of antisense nucleic acid mimics against E. coli
Mariana Gomes, Igor Resende, Yana Zamoshchak, Daniela Araújo, Joana Castro, Dinesh Dhumal, Ling Peng, Rita S Santos, Nuno F Azevedo
Journal of Controlled Release 384:113850 (2025)10.1016/j.jconrel.2025.113850
Blade-Coated All-Polymer Organic Solar Cells with 15% Efficiency Using Eco-Friendly Solvent Systems
Mohamed El Amine Kramdi, Aral Karahan, Lydia Abbassi, Takeshi Watanabe, Hidehiro Sekimoto, Olivier Margeat, Jörg Ackermann, Carmen Ruiz Herrero, Christine Videlot-Ackermann
ACS Applied Materials & Interfaces (2025)10.1021/acsami.5c12486
DDX5 mRNA-targeting antisense oligonucleotide as a new promising therapeutic in combating castration-resistant prostate cancer
Thi Khanh Le, Chaïma Cherif, Kenneth Omabe, Clément Paris, François Lannes, Stéphane Audebert, Emilie Baudelet, Mourad Hamimed, Dominique Barbolosi, Pascal Finetti, Cyrille Bastide, Ladan Fazli, Martin Gleave, François Bertucci, David Taïeb, Palma Rocchi
Molecular Therapy 33:5282 (2025)10.1016/j.ymthe.2025.08.041
Synthesis and Properties of Quinoidal (Di-)Anionic Coupled Polymethine-Oxonol Dyes and Their Aromatic Counterparts
Benjamin Mourot, Carmelo Naim, Olivier Siri, Denis Jacquemin, Simon Pascal
Organic Chemistry Frontiers 12:5770-5782 (2025)10.1039/D5QO00801H
Dendrimer engineering to overcome delivery challenges of nucleic acids
Qianqian Ni, Jing Wu, Christina Galanakou, Cheng-Cai Zhang, Donald A Tomalia, Ling Peng
Nature Reviews Bioengineering (2025)10.1038/s44222-025-00347-w
Impact of inner hydrophobicity of dendrimer nanomicelles on biodistribution: a PET imaging study
Tom Roussel, Twiany Cruz-Dubois, Beatrice Louis, Erik Laurini, Ling Ding, Laure Balasse, Vincent Nail, Françoise Dignat‐george, Suzanne Giorgio, Sabrina Pricl, Benjamin Guillet, Philippe Garrigue, Ling Peng
Journal of materials chemistry B 13 (2025)10.1039/D4TB01266F
Iridium Complexes based on 1H-imidazo[4,5f][1,10]phenanthroline ligand: Photophysical properties and Light-Emitting Electrochemical Cells characterization
Luis Sanhueza, Santiago Luco, Felipe Salas, Iván González, Stephania Robles, Mirco Natali, Anass Khodr, Olivier Margeat, Carmen Ruiz, Diego Cortés-Arriagada, Paulina Dreyse
Chemistry - A European Journal (2025)10.1002/chem.202502588
Electron Spin Dynamics of Single and Paired Methyl Radicals at the ZnO Nanoparticle Surface
Adrien Savoyant, D. Marin, Z. Jradi, O. Margeat, S. Bertaina
Journal of Physical Chemistry C 129:9778-9785 (2025)10.1021/acs.jpcc.5c01638
Bola-Amphiphilic Dendrimer Enhances Imatinib to Target Metastatic Ovarian Cancer via β-Catenin-HRP2 Signaling Axis
Zeyu Shi, Margarita Artemenko, Weiyu Yu, Ming Zhang, Canhui Yi, Peng Chen, Shuting Lin, Zhancun Bian, Baoping Lian, Fanzhen Meng, Jiaxuan Chen, Tom Roussel, Ying Li, Karen K L Chan, Philip P C Ip, Hung-Cheng Lai, Sally K Y To, Xiaoxuan Liu, Ling Peng, Alice S T Wong
ACS Applied Materials & Interfaces (2025)10.1021/acsami.4c12857
STING‐Activating Polymers Boost Lymphatic Delivery of mRNA Vaccine to Potentiate Cancer Immunotherapy
Miao Zhang, Yongling Wang, Benhao Li, Bowei Yang, Mengyao Zhao, Bingyu Li, Jianping Liu, Yaxin Hu, Zhaoming Wu, Yenhui Ong, Xiaolin Han, Lingwen Ding, Kongfu Zhu, Jianwei Li, Min Luo, Shengqi Chen, Ling Peng, Longjiang Zhang, Xiaoyuan Chen, Qianqian Ni
Advanced Materials (2025)10.1002/adma.202412654
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5 contrats ANR
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1 bourse Doc2AMU
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1 contrat de collaboration avec la société Dracula technologie
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1 projet AMidex
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1 équipe labellisée par la Ligue contre le Cancer
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2 contrats Horizon 2020